Protein Info for GFF4989 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Adenylate-forming enzyme

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 432 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details TIGR02304: putative adenylate-forming enzyme" amino acids 21 to 421 (401 residues), 278.2 bits, see alignment E=6.2e-87

Best Hits

KEGG orthology group: None (inferred from 54% identity to aex:Astex_2040)

Predicted SEED Role

"Adenylate-forming enzyme"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (432 amino acids)

>GFF4989 Adenylate-forming enzyme (Hydrogenophaga sp. GW460-11-11-14-LB1)
MHVGYLAAAAAFGRTRWLAASLRSRPQLEAYQAMRVRALLAHAQRHFTHYRNSSPSSLAA
LPIMDKPQLLANFQACNRAGITLESVRETLASGNEALSGHVVGQSTGTSGNRGYYVITDA
ERYAWLGTLLAKALPDALWRRHRVALALPGLSRLYRSASSGSRISLAYFDLAQGVDAWLD
AFKRFDADTIVAPPKVLRHLAERGVLRSERIFSGAEVLDPLDRESIEHHARTQVREIYMA
TEGLFGVSCAHGTLHLAEDVVHFEWQRPSPDSSLRTPLVTDFTRRAQAMIRYRMNDLLAL
QAQPCPCGSILQPISRVEGRQDDVFWLQTSSGAWRMVTPDLIRNAIVDASSAIRDFRAVQ
TAPDRIEVMLPLDVPAGVEDRVLQALKSRLEDMAVGPVELTLGHTMDVPMDRKLRRVRRA
WTPPAAATHSQN