Protein Info for GFF4952 in Pseudomonas sp. DMC3

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 980 PF04313: HSDR_N" amino acids 7 to 193 (187 residues), 82.9 bits, see alignment E=7.1e-27 TIGR00348: type I site-specific deoxyribonuclease, HsdR family" amino acids 23 to 671 (649 residues), 426.9 bits, see alignment E=7.6e-132 PF04851: ResIII" amino acids 252 to 417 (166 residues), 85.2 bits, see alignment E=1.3e-27 PF00270: DEAD" amino acids 255 to 417 (163 residues), 25.1 bits, see alignment E=3.4e-09 PF18766: SWI2_SNF2" amino acids 256 to 482 (227 residues), 175.3 bits, see alignment E=3.9e-55 PF22679: T1R_D3-like" amino acids 586 to 659 (74 residues), 58.1 bits, see alignment 3.7e-19

Best Hits

KEGG orthology group: K01153, type I restriction enzyme, R subunit [EC: 3.1.21.3] (inferred from 89% identity to mfa:Mfla_1175)

Predicted SEED Role

"Restriction enzymes type I helicase subunits and related helicases (EC 3.1.21.3)" (EC 3.1.21.3)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.21.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (980 amino acids)

>GFF4952 hypothetical protein (Pseudomonas sp. DMC3)
MTSLWISEAGTVQFPMVKHAVEIGWTPITPEDARTKRGGEAGTFFRDVLEVKLAEFNPWL
SADASRSIVETLDALPTDIGGNRELLAWLRGERQWRDEAEQRHRPVTLIDFERVSNNMFH
VTWEWKIKPPARKGNRADMMFVVNGVPVVIVEHKNPKDGDGIERAIKQLRRYELETPELL
AKTQLFNVTHLLDYWYGVTWNTNRRDMARWKQEPEETYRFAVQAFFEPTDFLRTLQHWIL
FYEQDGETRKSVLRQHQRRAIDAILDRCSDHTKTRGLVWHTQGSGKTFTLLTAARLILEN
KKRFSNATVILVVDRTELEGQLKGWVERLLGEMQQQDIAIERADNKDKLQALLDADFRGL
IISMIHKFESIRRDSCPRTNVYVFIDEAHRSVAKNLGTYLMAAVPKATIIGFTGTPIDRT
SQGEGTFKIFGAEDEFGYLDKYSIAESIADETTLPIKHVMAPSEMTVPIERLDQEFFALA
ESEGVTDVEELNKVLDRAVGLRTFLTADDRIEKVSAFIAEHFRENVLPLGYKAFVVAVNR
EACAKYKKALDKLLPPEWTAPVYTENSADVVERPLIAELQLSYEAENQVRTLFKKPAENP
KILIVTDKLLTGYDAPPLYCLYLDKPMRNHVLLQSIARVNRPYVDGNGVQKRVGLVIDFV
GVLRELNKALKFDSSDVSGVIEDLDVLLQDFLLRIQQAQKDYLKVDASSSLDERLERLVF
GRFLAPEARKIFFESYKEIEALWEILSPDPALRDHIATYKQLSQLYATVRNAYAEKIGFV
ADLAYKTRRLIEESAEQHGLGRLTKSVTFDVATLNSLRAEDGSDEGKVFNLVRGLQHEID
EKPAAAPVLQPLKDRAERILKDLEERRTVGLAAMDQLAALAAEKDAAMKAASDSGLSAQA
FAVAWVLREDVAVKAAGIDPIMLAKDAEELLGRFPNASVNADEQRRLRALLYKPVLALAQ
GERGRVVDMVVRLLLAEGGK