Protein Info for GFF495 in Variovorax sp. SCN45

Annotation: Kup system potassium uptake protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 614 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 38 to 61 (24 residues), see Phobius details amino acids 90 to 108 (19 residues), see Phobius details amino acids 131 to 150 (20 residues), see Phobius details amino acids 161 to 182 (22 residues), see Phobius details amino acids 207 to 226 (20 residues), see Phobius details amino acids 238 to 259 (22 residues), see Phobius details amino acids 279 to 305 (27 residues), see Phobius details amino acids 326 to 350 (25 residues), see Phobius details amino acids 358 to 382 (25 residues), see Phobius details amino acids 388 to 410 (23 residues), see Phobius details amino acids 416 to 434 (19 residues), see Phobius details PF02705: K_trans" amino acids 2 to 537 (536 residues), 700.3 bits, see alignment E=7.9e-215

Best Hits

Swiss-Prot: 52% identical to KUP_BURM7: Probable potassium transport system protein kup (kup) from Burkholderia mallei (strain NCTC 10247)

KEGG orthology group: K03549, KUP system potassium uptake protein (inferred from 94% identity to vpe:Varpa_3426)

Predicted SEED Role

"Kup system potassium uptake protein" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (614 amino acids)

>GFF495 Kup system potassium uptake protein (Variovorax sp. SCN45)
MIAALGVVFGDIGTSPLYAFKETMNPEHGVPFSPDSVLGLLSLIFWGLMFVVTLKYVVFV
LRADHDGEGGILALQALARNAVAGPKTKPWVWNVIGMLGLVGAAMFYGDSLITPAISVLS
AVEGLEVQAPVLQKAVLPITVIILIGLFAVQKKGTGVVGKVFGPVMLLWFLILAAAGLWQ
VLQQPQVLAALDPRRALGFLVEHRAQSLAVLGAVFLAFTGGEALYADMGHFGARPIRLAW
LFIALPGLVLNYFGQGALVLGNPAAIDNPFFRLFPSWGVLPMVVLAAMATVIASQAVISG
AFSLTAQAMRMGYLPRMRVIQTSGTAIGQIYVPTVNWLLMVGVLLLVLGFRSSGALSAAY
GIAVSITMVTTTLLAGIVAWGLWRWNKVAVVVGAAAFVVVDLTFVVANSLKIAEGGWLTL
AVAVVVMVLFTTWAKGRRLGLEAAAAESLPLRPFFESLALHMPHRVSGTAVFLNPDATAV
PHALLHNLKHNQVLHEQVIVLRVQPSDTPRVDARNRIEAEQLMDGIWVVTAHHGFMERPD
VPEFMRILAYQKTLAIDSMKTSYFVSRASVGEENLPGMNPVRRALFGWLQRNAGRASDYF
ELPDNRLVEMGLRT