Protein Info for GFF4949 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 269 PF00005: ABC_tran" amino acids 28 to 170 (143 residues), 123.8 bits, see alignment E=4.1e-40

Best Hits

Swiss-Prot: 44% identical to SSUB2_BURL3: Aliphatic sulfonates import ATP-binding protein SsuB 2 (ssuB2) from Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)

KEGG orthology group: K02049, sulfonate/nitrate/taurine transport system ATP-binding protein (inferred from 77% identity to vpe:Varpa_5416)

Predicted SEED Role

"ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component" in subsystem Alkanesulfonate assimilation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (269 amino acids)

>GFF4949 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component (Hydrogenophaga sp. GW460-11-11-14-LB1)
MKTDQSSAAPAIDIQGVQKTYPNGTVALQPVDLTVREGEFVTLLGPSGCGKSTLLKMIAG
LLEPTSGSLKLWGQGVNQLEQSGHRLAFVFQSPTLMPWASVQTNVRLPLDLAGVPRAEAD
ARVADALALVGLSKFAKALPRALSGGMQMRVSIARGLVVEPTLLLMDEPFGALDXITRHK
LDADLLELWQKKNLSVVFVTHSIHEAVFLSSRVVMMAARPGRIVEEFQIDQPYPRTPDFM
VSTEFSHYAKQLQDSLLRASRDTTESAHA