Protein Info for GFF4944 in Variovorax sp. SCN45

Annotation: Excinuclease ABC subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1032 TIGR00630: excinuclease ABC subunit A" amino acids 39 to 661 (623 residues), 838.1 bits, see alignment E=5.3e-256 PF17760: UvrA_inter" amino acids 166 to 271 (106 residues), 120.5 bits, see alignment E=1.1e-38 PF17755: UvrA_DNA-bind" amino acids 328 to 440 (113 residues), 119.5 bits, see alignment E=3e-38

Best Hits

Predicted SEED Role

"Excinuclease ABC subunit A" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1032 amino acids)

>GFF4944 Excinuclease ABC subunit A (Variovorax sp. SCN45)
LNSKATELAAAEAAEAAERARDAERERDAYLGAVLAQQRISIRGARTHNLKNVDLDIPRN
KLVVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLQLMDKPDVDVIEGLSPAIS
IEQKATSHNPRSTVGTVTEIHDYLRLLYARAGTPYCPDHHLPLQAQTVSQMVDAVLAIPD
EPRLMILAPVAREKKGEFVELFAEMQAAGYVRFRVDGQTYEYNDLPKLKKTEKHDIDIVI
DRLRARPDMQQRLAESFEAALRMAEGRAIALELGAEGAPDKEHLFNAKFACPICHYSLSE
LEPRLFSFNSPVGACPSCDGLGHREVFDPARVVAFPSLSLASGAIKGWDRRNGYYFSMIE
SVAKHYKFDVDAPFESLPASVQQVLLHGSAAEEIKFNYTMESGNFAGKKLTKKHPFEGII
PNMARRYRETDSVMVREDLARFRNLQPCPDCGGSRLRREARNVFLVDESARPADGGEPPR
MAIFELSHLTLRDSLAWFQTLKLRGAKADIADKVVREIGLRLKFLNDVGLNYLSLDRSAE
TLSGGEAQRIRLASQIGSGLTGVMYVLDEPSIGLHQRDNDRLIGTLKHLRDIGNSVIVVE
HDEDMIHAADHVIDMGPGAGVHGGRVMAQGTYAEVSANPDSLTGQYLSGTRKIEVPRHRT
AWLPVVSKPAFNEGKKPSRFPQSPAAERRAAREAAHLATQTDLQEIRVVGATGNNLKNVS
VAFPVGLLTCVTGVSGSGKSTLVNDTLYTAVARTLYRAHEEPAAHESVEGIEYFDKVINV
DQSPIGRTPRSNPATYTGLFTPIRELMAETNTARERGYGPGRFSFNVAGGRCEACQGDGV
VKVEMHFLPDVYVPCEVCHGQRYNRETLEVLYKGKNIAQILEMTVETAHEFLKAVPTIER
KLRTLLDVGLSYIKLGQSATTLSGGEAQRVKLALELSKRDTGRTLYILDEPTTGLHFADI
ELLLKVLHQLRDAGNTIVVIEHNLDVIKTADWLIDMGPEGGAGGGTVVGEGTPEDIAANE
ASHTGRYLKRLL