Protein Info for GFF4927 in Variovorax sp. SCN45

Annotation: Citrate-proton symporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 431 transmembrane" amino acids 31 to 55 (25 residues), see Phobius details amino acids 63 to 88 (26 residues), see Phobius details amino acids 98 to 120 (23 residues), see Phobius details amino acids 122 to 122 (1 residues), see Phobius details amino acids 130 to 153 (24 residues), see Phobius details amino acids 165 to 188 (24 residues), see Phobius details amino acids 197 to 216 (20 residues), see Phobius details amino acids 247 to 269 (23 residues), see Phobius details amino acids 281 to 300 (20 residues), see Phobius details amino acids 311 to 331 (21 residues), see Phobius details amino acids 337 to 356 (20 residues), see Phobius details amino acids 377 to 399 (23 residues), see Phobius details amino acids 405 to 425 (21 residues), see Phobius details PF00083: Sugar_tr" amino acids 27 to 221 (195 residues), 63.8 bits, see alignment E=1.5e-21 amino acids 221 to 419 (199 residues), 31.2 bits, see alignment E=1.2e-11 PF07690: MFS_1" amino acids 60 to 289 (230 residues), 49.6 bits, see alignment E=2.9e-17 amino acids 284 to 420 (137 residues), 36.5 bits, see alignment E=2.7e-13

Best Hits

KEGG orthology group: K03762, MFS transporter, MHS family, proline/betaine transporter (inferred from 57% identity to bpt:Bpet4885)

Predicted SEED Role

"Citrate-proton symporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (431 amino acids)

>GFF4927 Citrate-proton symporter (Variovorax sp. SCN45)
MSTLAPRAAELSDPAEPASRQSTLRVITAISIGNALEWFEIVIYGFLAVTISKLFFPAEN
DTVSLLITLGTFGVTFVMRPVGSLVLGAYADARGRKNALTLSMALMLLGTLLIAVSPTFA
QIGLWAPGLVILARLLQGFAAGGEFGSATALLAEQDPRRRGFFSSWQFASQGITTFLAAG
FGMGLNALLTPEQLLSWGWRIPFFFGLLIGPAGLYIRRHLDEGMEFKRAAQEATPVRTTL
VDQRGRTLAAMGLIILATIVAYTGLFMPTFAVRQLGLPPSMAFAGTFWFGVLQFALVPLF
GSMSDRVGRVVIMRGAALVMLVMIVPLFYLLVNHPSVPALMLALTAMGVVASAYWGPISA
AMSELFPAATRGTGLSVSYSFGVAIFGGFAPFISAWLITATGSKIAPAFYVGFGVLVSLA
ALRAARRYGVK