Protein Info for PS417_25115 in Pseudomonas simiae WCS417

Annotation: lipopolysaccharide biosynthesis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 738 transmembrane" amino acids 37 to 61 (25 residues), see Phobius details amino acids 454 to 477 (24 residues), see Phobius details PF02706: Wzz" amino acids 22 to 113 (92 residues), 47.1 bits, see alignment E=2.5e-16 PF13807: GNVR" amino acids 403 to 474 (72 residues), 48.7 bits, see alignment E=6e-17 TIGR01007: capsular exopolysaccharide family" amino acids 525 to 720 (196 residues), 132.4 bits, see alignment E=7.8e-43

Best Hits

Predicted SEED Role

"Tyrosine-protein kinase Wzc (EC 2.7.10.2)" in subsystem Colanic acid biosynthesis (EC 2.7.10.2)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.10.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7USC8 at UniProt or InterPro

Protein Sequence (738 amino acids)

>PS417_25115 lipopolysaccharide biosynthesis protein (Pseudomonas simiae WCS417)
MRNTAAVPDSAPHIQRQVEDDLIDLLKFWRIIWGRKWSIFGLVFVISLVAALAAFTVTPI
YRAVASLLIEEKAAKVLSIEQIYGADGSSSEYLQTQFELLKSRALAERVVTELKLVDNRE
FDPRQQPTPLLDIAAWKKSLSGLFGVPPAPLDGLEEQTKRFDEVTRAFMERVKVEPQGKS
KLVKVQVEMADPRLAMVAANALANGFIERQLEASQGVSLAAGSWMSSRLDELRGQLKDSE
ELLQRYREAENLVDVGGVGTISAAELAQTGDRMIDARRQRAEAESQYRQVQSIARNDWQR
LGSVPAVLGHPLIQQFKADEARARAKVEELSKRYGARHPAMEAARSELSAASGSLRGQIE
QVVAGIERNYQLAQANQTSLQSSFDANKSRIQEISRKEFKLRELQREVDANRTLYETFTN
RLKETAATSDLNSVTARVVDPAVLPDKPAKPHKALIVFIAAMLTFFVAAGLTLLLDALNN
TFKTAQQIEDHLNISVLGVMPLVEKSYRNQMSQVFHRNLDRRFSEAVRSIRTGIVLSGID
NPHQVLLVTSSVPAEGKSALSISLACALGQLDRVLLIDADMRRPSLAKSFQFPAGTPGLA
NLLAGTATEQECIRQVNGIDVLCAGSVPPNPLELLSSPRFAALLNDLKGRYQRIIFDSAP
TQVVSDALHLSTYVDFVIYVSKWAATPIPLVEKGIGQLLQNKAPVKGIVLNQMDFDQAKA
DGQSYDGYYEYHDESRAT