Protein Info for GFF4893 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Nitrogen regulation protein NR(I)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 208 PF06490: FleQ" amino acids 10 to 120 (111 residues), 22.4 bits, see alignment E=2e-08 PF00072: Response_reg" amino acids 10 to 119 (110 residues), 98.8 bits, see alignment E=3.4e-32 PF00196: GerE" amino acids 145 to 197 (53 residues), 67.4 bits, see alignment E=9.7e-23

Best Hits

Swiss-Prot: 45% identical to FIXJ_BRADU: Transcriptional regulatory protein FixJ (fixJ) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: None (inferred from 87% identity to rfr:Rfer_2210)

Predicted SEED Role

"Nitrogen regulation protein NR(I)" in subsystem Ammonia assimilation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (208 amino acids)

>GFF4893 Nitrogen regulation protein NR(I) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSLIPKKGSVYVVDDDEAVRDSLQWLLEGKDFRVRCFESAEAFLSRYDAREVACLIADIR
MGGMTGMELQERLIERQSPLPIVFITGHGDVPMAVESMKRGALDFIQKPFKEDQLVALVE
RMLEHAREAFATHQQAVSRDALLSKLTSREAQVLERIVAGRLNKQIADDLGISIKTVEAH
RANIMEKLGANTVADLLKIALGQTPAKA