Protein Info for GFF4874 in Hydrogenophaga sp. GW460-11-11-14-LB1
Annotation: ATPase component BioM of energizing module of biotin ECF transporter
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K06916, (no description) (inferred from 76% identity to aav:Aave_3245)Predicted SEED Role
"ATPase component BioM of energizing module of biotin ECF transporter" in subsystem Biotin biosynthesis or ECF class transporters
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (365 amino acids)
>GFF4874 ATPase component BioM of energizing module of biotin ECF transporter (Hydrogenophaga sp. GW460-11-11-14-LB1) LSVRSRYEAALKERGYTTDPAQQRAIDALERCASEWAVYKQKRSNSLKKLFVNPEIPRGV YMYGGVGRGKSFLMECFFEAVPLRRKTRLHFHEFMREVHRELRELQGTVNPLDELGARIA KRYKLICFDEFHVADVTDAMILHRLLDALFKAGVGFVTTSNFRPDDLYPDGLHRDRILPA IELLKQRLEVLNVDNGTDYRQRTLNHIQLYHWPLGPQADEAMETTFQELAEMGDQDAVMH IEARQIQALRRAGGVIWFDFRTLCGGPRSQNDYLEIASQFHTLMLSNVPQMSVRQASEAR RFTWLVDVLYDRRVKLVMSAAVPPEQLYQEGPMSHEFPRTVSRLTEMQSQEFLSLEHRLV DTGLT