Protein Info for GFF4872 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: DinG family ATP-dependent helicase YoaA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 679 PF00270: DEAD" amino acids 37 to 89 (53 residues), 25.2 bits, see alignment 1.2e-09 PF13307: Helicase_C_2" amino acids 489 to 648 (160 residues), 131 bits, see alignment E=4.7e-42

Best Hits

Predicted SEED Role

"DinG family ATP-dependent helicase YoaA" in subsystem DNA repair, bacterial DinG and relatives

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (679 amino acids)

>GFF4872 DinG family ATP-dependent helicase YoaA (Hydrogenophaga sp. GW460-11-11-14-LB1)
LSELENGVAAAFAADGPLARAHGHLRPRQGQLDMAAAVARAIENGHGLAVEAGTGVGKTF
AYLVPLLLSGRRALLSTATQALQDQLFARDIPAVVRALGLPVRVALLKGRSSYVCLHRLE
QALHGPASAGPRDPAISAGLTQVLHWAHRSRSGDLAELEALDERSPLRPLITSTRDNCLG
ASCPRHGECHVNRARGEALQAEWVVINHHLFFSDQLLLETGVASLLPAADVVVFDEAHQL
NDTGIPFLGRTLGAGQLRELARDLATQGAQWARGQRPWAHLALAIEQASRAMAALPRQAS
ASGGRHRWHGAAPEGVDTLAWQRGIANLGQALAAALAALTATAQAAAELERLRVRVQALQ
TVWDDMGFGPSAAQASEMVRWVEWGEGRHWRIVCAPPDSSRLFQSLLDEAPGRRSWVFSS
ATLGDDAELSWFTRGLGLDALGLQTLRVPSPFDHATQAALYVPHDLPEPADASHTPALAD
AVARWASRLGGRTLVLTTTLKAASRMAEHLQGLVAQGRCAPLRVLAQGRLSKRALLARFR
EGSEPSVLVASASFWEGVDLAGDALQLLVIDKLPFAPPDDPLMQARGQRLEAQGLSAFND
AFLPEAAMALKQGAGRLIRAETDQGILVIGDRRLITRSYGNRLLEALPAMRRLVDETDME
AGLDALVLTRSSTKDRPWI