Protein Info for GFF4857 in Variovorax sp. SCN45

Annotation: benzoate MFS transporter BenK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 455 transmembrane" amino acids 22 to 46 (25 residues), see Phobius details amino acids 57 to 79 (23 residues), see Phobius details amino acids 87 to 105 (19 residues), see Phobius details amino acids 112 to 133 (22 residues), see Phobius details amino acids 144 to 165 (22 residues), see Phobius details amino acids 174 to 195 (22 residues), see Phobius details amino acids 255 to 276 (22 residues), see Phobius details amino acids 287 to 312 (26 residues), see Phobius details amino acids 319 to 337 (19 residues), see Phobius details amino acids 343 to 366 (24 residues), see Phobius details amino acids 379 to 403 (25 residues), see Phobius details amino acids 410 to 428 (19 residues), see Phobius details PF07690: MFS_1" amino acids 27 to 315 (289 residues), 136.1 bits, see alignment E=2.1e-43 amino acids 299 to 438 (140 residues), 42.2 bits, see alignment E=7.5e-15 PF00083: Sugar_tr" amino acids 31 to 401 (371 residues), 94.7 bits, see alignment E=9.3e-31 PF06779: MFS_4" amino acids 43 to 188 (146 residues), 36.9 bits, see alignment E=4.2e-13

Best Hits

Swiss-Prot: 41% identical to BENK_ACIAD: Benzoate transport protein (benK) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)

KEGG orthology group: K05548, MFS transporter, AAHS family, benzoate transport protein (inferred from 100% identity to rpi:Rpic_2637)

Predicted SEED Role

"benzoate MFS transporter BenK" in subsystem Benzoate degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (455 amino acids)

>GFF4857 benzoate MFS transporter BenK (Variovorax sp. SCN45)
VCQIDMQKLADDARFNRFHAKVLLWCLLILIIDGYDIAVVGIALPSIMQQMGVNASTAGF
MASSALFGMMFGAMVLGTLSDRIGRRWALSIGVMLFSVFTAAAGFTKDPISFSVVRFIAG
LGIGGVLPVIVAQMVEYSPKKIRSLMTALMTSGYALGGILAAVLGKQLIGEYGWQVVFIA
AGVPVLLIPFILKLVPESMTYLISRSRNGELAEVARNLQPGVKHPADAQFVVPTADRVAG
APVSRLFQDGRGPSTVLFWIAFFSGLFMVYALSSWLTKLMAMAGYSLGSALSFVIALNVG
AIIGAVGGGWLADKFNIKWVLVGMYALGGVLLYLMTFQTSTELRYLIIGAVGACTTGAQL
VAYAYCGQFYPMSIRSTGIGMASGVGRLGAIAAPLLIGQIVALELPLEQNFLVIGAFGII
GSIALAFIRHGGPASVGPQEAARELRPSQQTPQNA