Protein Info for GFF4789 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Lipoprotein NlpD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 319 PF01476: LysM" amino acids 63 to 105 (43 residues), 45 bits, see alignment 8.3e-16 PF01551: Peptidase_M23" amino acids 219 to 312 (94 residues), 114.2 bits, see alignment E=2.6e-37

Best Hits

Swiss-Prot: 100% identical to NLPD_SALTY: Murein hydrolase activator NlpD (nlpD) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K06194, lipoprotein NlpD (inferred from 99% identity to sek:SSPA2593)

MetaCyc: 87% identical to murein hydrolase activator NlpD (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Lipoprotein NlpD"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (319 amino acids)

>GFF4789 Lipoprotein NlpD (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MGATTQQTPQQAPQIQPVQRPVTQPMQTQPVTEQPVQMENGRIVYNRQYGNIPKGSYTGG
STYTVKKGDTLFYIAWITGNDFRDLAQRNSISAPYSLNVGQTLQVGNASGTPITGGNAIT
QADAAQQGVVTRSAQNSTVAVASQPTITYSEGSGEQSANKMLPNNKPAGTVVTAPVTAPT
VSTTEPNASSTSTSAPISAWRWPTDGKVIENFGASEGGNKGIDIAGSKGQAIVATADGRV
VYAGNALRGYGNLIIIKHNDDYLSAYAHNDTMLVREQQEVKAGQKIATMGSTGTSSTRLH
FEIRYKGKSVNPLRYLPQR