Protein Info for GFF4786 in Variovorax sp. SCN45

Annotation: Beta-lactamase class C-like and penicillin binding proteins (PBPs) superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 487 signal peptide" amino acids 1 to 41 (41 residues), see Phobius details PF00144: Beta-lactamase" amino acids 63 to 365 (303 residues), 144.5 bits, see alignment E=2.2e-46

Best Hits

KEGG orthology group: None (inferred from 82% identity to vpe:Varpa_3990)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (487 amino acids)

>GFF4786 Beta-lactamase class C-like and penicillin binding proteins (PBPs) superfamily (Variovorax sp. SCN45)
MRLLPRAMIRATTRATIRSIPRRWLVAWLLAPLLAGTAAAQLQPLTLASDPAFIAKAALG
AERGTLVVGTLRNGKPAYGAAYNPEPPSAPRAIEPSSAEQPMFEIGSITKVFTGLLLAQA
VERGDLKLDDTVGKLLAGKVEGLSAPVASVTLRQLVTHTGCMPVMADGVGGGAPLAEQFR
SFDKPMFWAALARIKLTAAAPPCEGAYSNFGMALLGQLLAEHYGTSWGELVRARITEPLG
MNDTVITLGDKASRMAPAFAGDRRQPLFDMQAYAPASALRSTAADMMTFSRAIIAGAGGP
LGPAAARMLTPLAHYEGAWIGYAVMVRGPEGGRRTYWHAGLTEGYRTLWLIAPDTNEAIV
VLSSNARAPLQPVMLAIGKSRYPVPTTEVPIDPQRLDDYRGEFRINKTKALSFTVRGSKL
LVRETGRGYNALTPTGTDRFAVVGIGAQFVFRRDAANAVVAVSLTQGGSQLDARREGVAA
AAVPLQQ