Protein Info for PS417_24465 in Pseudomonas simiae WCS417

Annotation: metallopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 295 transmembrane" amino acids 33 to 50 (18 residues), see Phobius details PF04228: Zn_peptidase" amino acids 1 to 290 (290 residues), 412 bits, see alignment E=8.1e-128

Best Hits

Swiss-Prot: 53% identical to YPFJ_ECOL6: Uncharacterized protein YpfJ (ypfJ) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K07054, (no description) (inferred from 100% identity to pfs:PFLU5371)

Predicted SEED Role

"YpfJ protein, zinc metalloprotease superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U1P5 at UniProt or InterPro

Protein Sequence (295 amino acids)

>PS417_24465 metallopeptidase (Pseudomonas simiae WCS417)
MLWKKGRRSDNVVDARDDSGGGGGGMRFGGGKGLSLTAIVLIVGIGWMTGQDPLQILGQL
TGQMEQAPSVSTQSRQAPPANDEQADFVRAVLGDTEDTWGQVFKENGLAYKNPKLILFRG
RVNSACGGATSASGPFYCPADQQVYLDLDFFREMSQRFQAAGDFAQAYVIAHEVGHHVQT
LLGISSKIQAARQQGRQMQGDGGLLVRQELQADCFAGVWANRAQKRLNWLEPGDIEEALN
AANAIGDDRLQQQGQGRVVPDSFTHGTSAQRVRWFKTGFAQGQITQCDTFTAKSL