Protein Info for PS417_24400 in Pseudomonas simiae WCS417

Annotation: peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 578 transmembrane" amino acids 20 to 42 (23 residues), see Phobius details amino acids 54 to 76 (23 residues), see Phobius details amino acids 130 to 171 (42 residues), see Phobius details amino acids 251 to 277 (27 residues), see Phobius details TIGR01842: type I secretion system ATPase" amino acids 12 to 552 (541 residues), 782.8 bits, see alignment E=8.7e-240 PF00664: ABC_membrane" amino acids 20 to 279 (260 residues), 51.2 bits, see alignment E=1.5e-17 PF00005: ABC_tran" amino acids 345 to 492 (148 residues), 103.5 bits, see alignment E=1.5e-33

Best Hits

Swiss-Prot: 62% identical to APRD_PSEAE: Alkaline protease secretion ATP-binding protein AprD (aprD) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K12536, ATP-binding cassette, subfamily C, bacterial HasD (inferred from 95% identity to pfs:PFLU5358)

Predicted SEED Role

"ABC exporter for hemopore HasA, ATP-binding component HasD" in subsystem Protein secretion by ABC-type exporters

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UL93 at UniProt or InterPro

Protein Sequence (578 amino acids)

>PS417_24400 peptidase (Pseudomonas simiae WCS417)
MRHAGNETLAALKAYKSGFFNIGLFSAVINLLMLAPALYMLQVYDRVLASGNQMTLLMLT
LMILGLFGLMGALEWVRSQVVIRLGTQMDMRLNQRVYDAAFEAQLKGGTQAAGQALHDLT
TLRQFATGQALFAFFDAPWFPVYLLVIFLFHPWLGLLALVGAVLLIVLAWVNHHVSQAPM
ALASQLSINASQQATANLRNADTIEAMGMLATLRARWFGQHQAFLAQQNLASEKTATVTA
WSKGVRLALQSLVLGLGALLAVQGDITPGMMIAGSILMGRVLSPIDQLIGVWKQWGSARL
AFDRLSQMLEANPARPERMTLPVPKGQLSVEQISACAPGSRRPALANLGFNLAAGEVLGV
IGPSGCGKSTLARILVGAWGPLAGKVRLDGADLALWDKQQLGPHIGYLPQDIQLFAGSIA
QNIARFTEVDADKVFAAAQLAGVHELILQLPQGYDTHLGEGGAGLSGGQKQRVALARALY
GLPALIVLDEPNANLDEGGEHALLRAIAQLKQQRRTIILITHKPNVLSLTDQLLILKDGQ
MQSFGPTARVLEARQKPAAAKPVSTMSMSYRLGEGKQA