Protein Info for GFF4763 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Type III secretion outermembrane contact sensing protein (YopN,Yop4b,LcrE)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 372 TIGR02568: type III secretion regulator YopN/LcrE/InvE/MxiC" amino acids 32 to 269 (238 residues), 233.5 bits, see alignment E=1.5e-73 PF07201: HrpJ" amino acids 51 to 211 (161 residues), 149.7 bits, see alignment E=5e-48

Best Hits

Swiss-Prot: 100% identical to INVE_SALTY: Invasion protein InvE (invE) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K04058, type III secretion protein SctW (inferred from 99% identity to ses:SARI_00076)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (372 amino acids)

>GFF4763 Type III secretion outermembrane contact sensing protein (YopN,Yop4b,LcrE) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MIPGSTSGISFSRILSRQTSHQDATQHTDAQQAEIQQAAEDSSPGAEVQKFVQSTDEMSA
ALAQFRNRRDYEKKSSNLSNSFERVLEDEALPKAKQILKLISVHGGALEDFLRQARSLFP
DPSDLVLVLRELLRRKDLEEIVRKKLESLLKHVEEQTDPKTLKAGINCALKARLFGKTLS
LKPGLLRASYRQFIQSESHEVEIYSDWIASYGYQRRLVVLDFIEGSLLTDIDANDASCSR
LEFGQLLRRLTQLKMLRSADLLFVSTLLSYSFTKAFNAEESSWLLLMLSLLQQPHEVDSL
LADIIGLNALLLSHKEHASFLQIFYQVCKAIPSSLFYEEYWQEELLMALRSMTDIAYKHE
MAEQRRTIEKLS