Protein Info for GFF4738 in Variovorax sp. SCN45

Annotation: Response regulator NasT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 438 PF08376: NIT" amino acids 50 to 293 (244 residues), 188.6 bits, see alignment E=2.5e-59 PF03861: ANTAR" amino acids 372 to 423 (52 residues), 68.7 bits, see alignment 3e-23

Best Hits

KEGG orthology group: None (inferred from 79% identity to vpe:Varpa_4036)

Predicted SEED Role

"Response regulator NasT" in subsystem Nitrate and nitrite ammonification

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (438 amino acids)

>GFF4738 Response regulator NasT (Variovorax sp. SCN45)
MLQCRCKAPQAHAPTMKSGLSFLIAARRCEIDELDQLARTSELVGLIGRLVHALQRERGM
SNVFLASHGVRLAEQRAPQIAECLALEQEVRAGFDQLEAEHHRGLGSGNGARLFSRIAWV
LPGLDALPALRRRIDALELRPSQSTAAFVKLIAGLLSVVFEAADGATDPEISRLLVAMFN
FMQGKEFAGQERAFGAAALAMGRSDETRRLQWQHLIESQERCFQVFIDFSGDAVLALWRE
SQSDATMAELERMRRRGATSAPADAALGQAWFDCCTRRIDAMRTVEDRLAADLRALCSHK
TARARSELLTYRQVLDTLAPQTGAALFFDDADADAQAATPAQLGRHLERSVLDMVQEQSH
RLQAMSDELQTVRASLNERKLVERAKGLLMAHRRMSEQEAHKMLRETAMNQGRRLVEVAE
SVLAMADYLSMPERTPPR