Protein Info for GFF4721 in Variovorax sp. SCN45

Annotation: ABC transporter, permease protein 1 (cluster 1, maltose/g3p/polyamine/iron)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 305 transmembrane" amino acids 27 to 48 (22 residues), see Phobius details amino acids 91 to 113 (23 residues), see Phobius details amino acids 124 to 145 (22 residues), see Phobius details amino acids 172 to 195 (24 residues), see Phobius details amino acids 231 to 254 (24 residues), see Phobius details amino acids 274 to 296 (23 residues), see Phobius details PF00528: BPD_transp_1" amino acids 105 to 292 (188 residues), 36.3 bits, see alignment E=2.5e-13

Best Hits

KEGG orthology group: K02054, putative spermidine/putrescine transport system permease protein (inferred from 95% identity to vpe:Varpa_4052)

Predicted SEED Role

"ABC transporter permease protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (305 amino acids)

>GFF4721 ABC transporter, permease protein 1 (cluster 1, maltose/g3p/polyamine/iron) (Variovorax sp. SCN45)
VSAPATRASVAATPVHAVKAWWQAAPFALVFLLFFLIPLALVAMVSLWNFNEYELIPAVT
LRNYLSLFEGCSRLTDNGDLCVTLNTYLSTFKFCVLVWGITLLIGFSVAYFLAFHVRSST
MQTVLFVLCTVPFWTSNVIRMISWVPLLGRNGLVNQALMGVGLANQPVEWLLFSDFSVVL
AFVHLYTMFMIVPIFNSMMRIDRSLLEAASDAGASGWQTLWNVVVPLSRTGILIGSIFVI
TIVMGDFVTIGVMGGQQIASIGKIIQVQTSYLQFPLAAANAMILLAVVLMIIWGLTRLVD
IRKEL