Protein Info for GFF4710 in Xanthobacter sp. DMC5

Annotation: Sodium/glutamate symporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 402 transmembrane" amino acids 7 to 30 (24 residues), see Phobius details amino acids 41 to 64 (24 residues), see Phobius details amino acids 71 to 87 (17 residues), see Phobius details amino acids 97 to 124 (28 residues), see Phobius details amino acids 131 to 151 (21 residues), see Phobius details amino acids 163 to 187 (25 residues), see Phobius details amino acids 220 to 238 (19 residues), see Phobius details amino acids 249 to 269 (21 residues), see Phobius details amino acids 281 to 304 (24 residues), see Phobius details amino acids 311 to 333 (23 residues), see Phobius details amino acids 342 to 364 (23 residues), see Phobius details amino acids 376 to 401 (26 residues), see Phobius details PF03616: Glt_symporter" amino acids 10 to 373 (364 residues), 346.7 bits, see alignment E=6.6e-108 TIGR00210: sodium/glutamate symporter" amino acids 13 to 400 (388 residues), 394 bits, see alignment E=3.2e-122

Best Hits

KEGG orthology group: K03312, glutamate:Na+ symporter, ESS family (inferred from 82% identity to xau:Xaut_0831)

Predicted SEED Role

"Sodium/glutamate symporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (402 amino acids)

>GFF4710 Sodium/glutamate symporter (Xanthobacter sp. DMC5)
MPATYEVSGLLSFTIAILVYFLGAGLNEIIAPLKRWNIPEAVTGGILAALATLFAYKVVG
LAVSFDLDARDLLLLYFFTGIGLNARVSDLSTGGKPLVILLLLTVTYLALQNVVAVGGAA
ALGLPHGVGPLLGSVSLVGGHGTTIAWAPLISQRFALPNALEIGIASATLGLVIASLVGG
PVAGLLISRFNLRGTGDDAPMVGLPDTPAEPEGGSVDYKNILVTILALNLVIIIGYALEG
VVEKTGLKLPMFVVCMLVAIVITNILPKLAPRMPWPARTPALALVSDLSLKIFLAMSLMS
MQLWTLGGLGPALATVLGLQTLVAVAYILFVVFPAMGRNYQAAVLAAGFTGISLGATPTA
IANMTAVTRTHGPAPIAFIILPLVSAFFIDIANALAIGFMLR