Protein Info for GFF4705 in Xanthobacter sp. DMC5

Annotation: 6'''-hydroxyparomomycin C oxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 548 PF13450: NAD_binding_8" amino acids 11 to 63 (53 residues), 22 bits, see alignment 4.1e-08 PF00732: GMC_oxred_N" amino acids 198 to 317 (120 residues), 50.6 bits, see alignment E=5.8e-17 PF05199: GMC_oxred_C" amino acids 407 to 524 (118 residues), 64.9 bits, see alignment E=3.1e-21

Best Hits

KEGG orthology group: None (inferred from 85% identity to xau:Xaut_0822)

Predicted SEED Role

"Glucose-methanol-choline (GMC) oxidoreductase:NAD binding site" in subsystem Respiratory dehydrogenases 1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (548 amino acids)

>GFF4705 6'''-hydroxyparomomycin C oxidase (Xanthobacter sp. DMC5)
MAKATHCDVIVVGTGAGGGMLAYELAKAGLNVVSLEQGGRLADDHFKRVDPPGTQLDFGI
RANTVWPAEPHDSLFVHPLFEKGGDGSTGWPDNNFHHYQILAVNGLQNLWNGVSVRFSAR
DFRDWPISYSDLAPHYEAVERRIIVCGTEEHLEELPDGIYVPPKPLRPADMMIVDAVNAM
DEPYSHAIPNRKAIDTRPDSPNACVSTGICTSGCPTGAVYKFTARLLPEIENLPNYELRQ
GAKVVRLLREPGTKRVMGVEYRDMATGEARVLTADAVVLAAGAIESPRILFNSADEAAPE
GMGNAAGQLGLRLQDNPKAVLSTSLWKLWGKGRDFDIGYGDLLILMSRGWLPDGEEFPFI
GHAIHGVPDIPHYLAGMKRFPPFMKERLARFMFHSYVTLGLFCAGEPTPANRVRPGTTRD
RFGVRHVAVDFSATPRAEAMMEAMNGWGRQVLRHAGATSIYPSRDNTGTGIHYAGTTATT
ADPDRGVVDADLKLHDLDNVYVCDGGVIPVLPDKHLTLTIMALAHRLAGHLVEKARTGAA
VQGEPAHA