Protein Info for GFF4702 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Arabinose 5-phosphate isomerase (EC 5.3.1.13)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 PF01380: SIS" amino acids 26 to 157 (132 residues), 107.9 bits, see alignment E=3.5e-35 TIGR00393: sugar isomerase, KpsF/GutQ family" amino acids 30 to 298 (269 residues), 432.7 bits, see alignment E=2.9e-134 PF00571: CBS" amino acids 202 to 243 (42 residues), 19.7 bits, see alignment 8.8e-08 amino acids 252 to 304 (53 residues), 32.5 bits, see alignment 9e-12

Best Hits

Swiss-Prot: 100% identical to GUTQ_SALTY: Arabinose 5-phosphate isomerase GutQ (gutQ) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K02467, GutQ protein (inferred from 98% identity to sec:SC2771)

MetaCyc: 93% identical to D-arabinose 5-phosphate isomerase GutQ (Escherichia coli K-12 substr. MG1655)
Arabinose-5-phosphate isomerase. [EC: 5.3.1.13]

Predicted SEED Role

No annotation

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 5.3.1.13

Use Curated BLAST to search for 5.3.1.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (308 amino acids)

>GFF4702 Arabinose 5-phosphate isomerase (EC 5.3.1.13) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MLELQEASRLPERLGDDFVRAANIIIHCEGKVIVSGIGKSGHIGKKIAATLASTGTPAFF
VHPAEALHGDLGMIESRDVMLFISYSGGAKELDLIIPRLEDKSVALLAMTGKLHSPLGRA
AKAVLDISVEREACPMHLAPTSSTVNTLMMGDALAMAVMQARGFNEEDFARSHPAGALGA
RLLNNVHHLMRQGDAIPQVMLATSVMDAMLELSRTGLGLVAVCDEQHVVKGVFTDGDLRR
WLVGGGALTTPVSEAMTPNGITLQAQSRAIDAKELLMKRKITAAPVVDENGKLTGAINLQ
DFYQAGII