Protein Info for GFF4701 in Variovorax sp. SCN45

Annotation: Various polyols ABC transporter, permease protein 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 280 transmembrane" amino acids 14 to 35 (22 residues), see Phobius details amino acids 75 to 100 (26 residues), see Phobius details amino acids 112 to 136 (25 residues), see Phobius details amino acids 142 to 164 (23 residues), see Phobius details amino acids 190 to 212 (23 residues), see Phobius details amino acids 246 to 271 (26 residues), see Phobius details PF00528: BPD_transp_1" amino acids 92 to 257 (166 residues), 56.2 bits, see alignment E=2e-19

Best Hits

KEGG orthology group: K02026, multiple sugar transport system permease protein (inferred from 94% identity to vpe:Varpa_4068)

Predicted SEED Role

"Various polyols ABC transporter, permease component 2" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (280 amino acids)

>GFF4701 Various polyols ABC transporter, permease protein 2 (Variovorax sp. SCN45)
MSAVAKKKISVGTLFARLVLIVAGLSALVPVLWTFLNSFKNRVDIVSAVPKLFFTPTLEN
YVYVLSREAVAQGLVNSIVVVGAAVIVGALLGLPAAYALARYPLRWADDIQFFVLSMRFL
PPVAVAIPLMVIWLQLELYDTRFALIVTYTLLTLSTVIWLAIPAFKAVPKEVEEAGRVDG
YGPYAIFFKVALPIAARSLVGAIAFGFVLVWNEFLIALMLTTSDAKTLPIVASELSQLGR
DVPWGILNASVILLSLPPLLMVGVLSGFLNAAFKRKRDAA