Protein Info for GFF468 in Hydrogenophaga sp. GW460-11-11-14-LB1
Annotation: Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K02057, simple sugar transport system permease protein (inferred from 82% identity to vpe:Varpa_0277)Predicted SEED Role
"Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1)" in subsystem D-ribose utilization (TC 3.A.1.2.1)
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (365 amino acids)
>GFF468 Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1) (Hydrogenophaga sp. GW460-11-11-14-LB1) MRNILLPVGAILAALLLFGLFVSFAGVDPVEVWVLLFKGAFGDWYSWQNTLQRAAPLMLT ALCVAIPARAGLVVIGGEGALVLGGLASAALAHAVPLPAHLAGTVAVCLAGALAGALWIA LAGWLRQFRGINETISSLLLAYVAIGLFKHLVEGPLRDPASLNKPSTPALDEGLLIGGIA GSDVHWGLVIGIAVGLLAGLWLRLTPSGFSVQVVGGNPRAAQLVGLPATRLIIVACALGG AAAGLAGAIEVAAVHTSANAALIAGYGYAGILVSFIARHHPFAVVPVAIVFGGFGAAGSL LQRRLGLPDASVLLLQGIAFVLILASEALRDLDWKRVFDRLGQFGPSEPVPIVMPSPDTA KGEPR