Protein Info for GFF4672 in Variovorax sp. SCN45

Annotation: Exoenzymes regulatory protein AepA precursor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 561 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF07969: Amidohydro_3" amino acids 76 to 555 (480 residues), 396.3 bits, see alignment E=3.4e-122 PF01979: Amidohydro_1" amino acids 339 to 554 (216 residues), 36 bits, see alignment E=4.8e-13

Best Hits

KEGG orthology group: K07047, (no description) (inferred from 70% identity to reh:H16_B2473)

Predicted SEED Role

"Exoenzymes regulatory protein AepA precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (561 amino acids)

>GFF4672 Exoenzymes regulatory protein AepA precursor (Variovorax sp. SCN45)
MSQALFRKLLGALPVAAALACASAQAEPTVVAPVKGYTFAGDKLVSFEALAFDKGRVLGV
GEAATLAKQYPDARKIDGQGRALLPGLIDAHGHVFRVGFRQSEVVVTDTRTLAEAQAKIK
AYGQANPARQWIMGSGWNQVLWKLDRFPTAAELDAAIADRPVTLRRVDAHAIWANTKALQ
LAGITRDTPDPVGGRIERDAKGEPTGILIDKAQLLLTKVMPPYTDAERRLALDSALRHFA
SLGLTGVGDAGTGADEVRIYREFADAGKLSSRVYAMINDVGDDYKKLSTQGPLKGYADDR
FSLAAVKLFADGALGSRGAALLEPYSDDHNNKSLLFMDDAAMRAKVRTALKAGYQVNVHA
IGDAANRQILDAFEAAYKEDASGMARRNRVEHAQVVSLQDIPRFKTLGLIASMQPTHATS
DMNMAEDRVGKERIKGAYAWQTFLKQGTVIAGGSDFPVESANPFFGLHAAVTRTDHQGKP
IAGWHPEEAMTLPQALRAFTLDAAYAEHQEKTTGSLEPGKWADFIIVDQDPFTAAPGDIW
KTKVLGTWLAGEQVYAAPAAR