Protein Info for GFF4669 in Variovorax sp. SCN45

Annotation: Pca operon transcriptional activator PcaQ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 309 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details TIGR02424: pca operon transcription factor PcaQ" amino acids 8 to 305 (298 residues), 306.3 bits, see alignment E=9e-96 PF00126: HTH_1" amino acids 11 to 70 (60 residues), 68.8 bits, see alignment E=3.1e-23 PF03466: LysR_substrate" amino acids 100 to 300 (201 residues), 124.4 bits, see alignment E=4.3e-40

Best Hits

KEGG orthology group: K02623, LysR family transcriptional regulator, pca operon transcriptional activator (inferred from 86% identity to vap:Vapar_3572)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (309 amino acids)

>GFF4669 Pca operon transcriptional activator PcaQ (Variovorax sp. SCN45)
MSAMNFARLKLRHLQCLVMVAQERNLVRAAKALSLTQPAVSKTVAELEEIIGRPLLLRRR
RGVELTPAAEVLVRHAVSALRGLSEGLGLAMDMPEADQLHVAVGALPNMVANLLPEAVAL
LHASHPALRVRVVSGINAQLMTQLRQGEIDLVLGRLAQASAMADLAFEHLYSEPLLLVVR
PGHPLASRRKPALDALAGYPLVLPVSGSLIRHTADAFLIAQGVALPNRLVEATDTSFAIG
LLQRSEAVWFAPQGAVEGFLARGELKRVAIDTASTEGPVGLTVRRNSEPGEGARLLMETI
HGIVQKRKR