Protein Info for GFF4669 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Molybdenum ABC transporter, periplasmic molybdenum-binding protein ModA (TC 3.A.1.8.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 275 signal peptide" amino acids 1 to 48 (48 residues), see Phobius details PF12849: PBP_like_2" amino acids 48 to 258 (211 residues), 28.9 bits, see alignment E=1.5e-10 PF13531: SBP_bac_11" amino acids 50 to 272 (223 residues), 183.4 bits, see alignment E=8.8e-58 TIGR01256: molybdate ABC transporter, periplasmic molybdate-binding protein" amino acids 55 to 271 (217 residues), 192.2 bits, see alignment E=5.8e-61 PF01547: SBP_bac_1" amino acids 55 to 265 (211 residues), 76.8 bits, see alignment E=4.5e-25

Best Hits

KEGG orthology group: K02020, molybdate transport system substrate-binding protein (inferred from 59% identity to gpb:HDN1F_09750)

Predicted SEED Role

"Molybdenum ABC transporter, periplasmic molybdenum-binding protein ModA (TC 3.A.1.8.1)" in subsystem Molybdenum cofactor biosynthesis or Transport of Molybdenum (TC 3.A.1.8.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (275 amino acids)

>GFF4669 Molybdenum ABC transporter, periplasmic molybdenum-binding protein ModA (TC 3.A.1.8.1) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MLQENRCIAVYTWILRFTTFHETPMKTFATRSLTFVLAAGFAMASHAADVTVSAAASLTN
AFREIAPLFEAANPGTKVQLNFAASGALLQQIAKGAPADVFASADQETMDQAQSQGLVKE
AQRRNFVSNALVVIVPSASANVPKSTNDLAQSTYARIAIGLPASVPVGRYTKSVLEGAKL
WGAIEPKMIGATNVRQALDYVARGEVDAGFVYSTDAAIMLDKVKVAFTVPTPKPILYPVA
PLPAGPNAAEGAKFVDFLFTAPAQAILGKYGFGKP