Protein Info for GFF4665 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Putative deoxyribonuclease YcfH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 270 PF01026: TatD_DNase" amino acids 3 to 264 (262 residues), 259.7 bits, see alignment E=1.4e-81 TIGR00010: hydrolase, TatD family" amino acids 3 to 265 (263 residues), 263.5 bits, see alignment E=9.4e-83

Best Hits

KEGG orthology group: K03424, TatD DNase family protein [EC: 3.1.21.-] (inferred from 79% identity to pol:Bpro_2516)

Predicted SEED Role

"Putative deoxyribonuclease YcfH" in subsystem YcfH

Isozymes

Compare fitness of predicted isozymes for: 3.1.21.-

Use Curated BLAST to search for 3.1.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (270 amino acids)

>GFF4665 Putative deoxyribonuclease YcfH (Hydrogenophaga sp. GW460-11-11-14-LB1)
MFTDSHCHLSFPELRAQLPDILEAMSQAQVDRALCICTTLEEFEDVYSLARDHDHLWSTV
GVHPDSDEVQEPTLEDLLERAARPRVVGIGETGLDYYRLGERTVADMEWQRERFRVHIRA
ARQTSLPLVIHTRSSSDDTVAILREEGGFASDSRAGQGPAKGVFHCFTESMAVARAALDL
GFFISFSGILTFRNAADLREVAAYVPLDRTLIETDSPYLAPVPYRGKTNTPAYVPFVARQ
VAELKGLSVEAVAEATSRNFEQLFDQVVTT