Protein Info for PS417_23775 in Pseudomonas simiae WCS417

Annotation: exodeoxyribonuclease V subunit beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1224 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details TIGR00609: exodeoxyribonuclease V, beta subunit" amino acids 8 to 1204 (1197 residues), 1087.1 bits, see alignment E=0 PF00580: UvrD-helicase" amino acids 10 to 159 (150 residues), 79.6 bits, see alignment E=8e-26 amino acids 334 to 445 (112 residues), 91 bits, see alignment E=2.7e-29 PF13245: AAA_19" amino acids 17 to 432 (416 residues), 40.5 bits, see alignment E=7.9e-14 PF13361: UvrD_C" amino acids 696 to 837 (142 residues), 60.6 bits, see alignment E=4.6e-20 PF12705: PDDEXK_1" amino acids 1031 to 1182 (152 residues), 25.6 bits, see alignment E=2.9e-09

Best Hits

KEGG orthology group: K03582, exodeoxyribonuclease V beta subunit [EC: 3.1.11.5] (inferred from 79% identity to pba:PSEBR_a683)

Predicted SEED Role

"Exodeoxyribonuclease V beta chain (EC 3.1.11.5)" in subsystem DNA-replication (EC 3.1.11.5)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.5

Use Curated BLAST to search for 3.1.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UC18 at UniProt or InterPro

Protein Sequence (1224 amino acids)

>PS417_23775 exodeoxyribonuclease V subunit beta (Pseudomonas simiae WCS417)
MTSKPLALAFPLKGSQLIEASAGTGKTFTISALYLRLVLGHGGDESSFGRELLPPQILVV
TFTDAATKELRERIRIRLAEAARFFREEIEQPDALIADLRADYLPEQWPACANRLDIAAQ
WMDEAAVSTIHSWCQRMLREHAFDSGSLFTQTLETDHSDLLGEVLRDYWRLFCYPMHDDA
LNWVRSHWGGPAALMPRVRALFGSERPTDETREPAELITACLQERREALTTLKAPWQQWA
TELRDICLQAVAAKAVDGRKMQARYFEPWFEKISAWAADETLEQLDIGTGFTRLTPDGMA
EAWKGEPPQHPGIDAMAGLKAALDALPTPDAAVLQHAAGWVGKRFEEEKRRRAEMGFDDM
LIRLNAALQADGGERLASVVREQFPVALIDEFQDTDPVQYSIFDSIYRIEENHLDSGLFL
IGDPKQAIYAFRGADIYTYLRARQSTTGRHHTLGTNFRSSHAMVEAVNHVFQRAETGRGA
FLFREPDGVNPVPFHSVLSQGRKEQLQVDGQTLPAMNLWHLPTDQPVSNVIYRQQLAAAC
ATHIVELLNGGQQGSAGFLQPDGSFKGVRPSDIAILVRDGKEAQAVRGELAARGVRSVYL
SDKDSVFAAQEAHDLLAWLKACAEPDVERPLRAALACVTLNLSLAELERLNQDELAWESR
VMQFRGYRTIWRTQGVLPMLRRLLHDFKLPQTLIARSDGERVLTNLLHLSELLQQAASEL
DGEQALIRHLAEHLALSGQAGEEQILRLESDEQLVKVVTIHKSKGLEYDLVFLPFICSAK
PVDGSRLPLHYHDENGKSHVSLRPTPELIAQADNERLAEDLRLFYVALTRAKHACWLGIA
DLKRGNSNNSVLHLSALGYLLGAGASLGESAGLARWLLDLQEGCTAIHYGQVPEAQDNLF
HPPRNEATLRAPLLPKRKAAENWWIASYSALRIGDSMSAATLEAPESPQAQKLFDDERLD
PDAPREVAASGGDIHRFPRGPNPGTFLHGLLEWAGEDGFNVTPEAIEKAVGARCNRRNWE
GWIITLSSWLGHLLQTPLPVNNSHVSLSGLQQYQIEMEFWFASHKVDVLALDKLVCQYTH
NGVSRVAAEPVLLNGMFKGFIDLTFEHDGRYYVADYKSNWLGPDDSAYTFDAMEQSILDH
RYDLQYVLYLLALHRQLKARLPDYDYDRHVGGALYIFLRGTQSASQGAYFTRPPRELIEG
LDLLFQGKPIPPKVEPAWEQGVLL