Protein Info for GFF4630 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868
Annotation: Dolichol-phosphate mannosyltransferase (EC 2.4.1.83) in lipid-linked oligosaccharide synthesis cluster
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
No protein families (PFam or TIGRFam), signal peptides, or transmembrane helices were found in this protein.
Best Hits
KEGG orthology group: None (inferred from 100% identity to seh:SeHA_C0850)Predicted SEED Role
"Dolichol-phosphate mannosyltransferase (EC 2.4.1.83) in lipid-linked oligosaccharide synthesis cluster" (EC 2.4.1.83)
MetaCyc Pathways
- protein O-mannosylation II (mammals, core M1 and core M2) (1/5 steps found)
- protein O-mannosylation III (mammals, core M3) (1/5 steps found)
- protein O-mannosylation I (yeast) (1/8 steps found)
- protein N-glycosylation (Haloferax volcanii) (1/11 steps found)
- protein N-glycosylation initial phase (eukaryotic) (1/19 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.4.1.83
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (649 amino acids)
>GFF4630 Dolichol-phosphate mannosyltransferase (EC 2.4.1.83) in lipid-linked oligosaccharide synthesis cluster (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868) MDMNFKKYKTVSFDIFDTLVSRRIYRPRDLFSLMQSTLATEKFFISAYEIGIIDNFPEIR VQAEVSARENRVRRFGGEPEILISEIYDEILKKHPQLSPATVKKIIDLEIQMEKIVLYKN ARGSCLFEKAISDGCKVILISDMYLPSAILKELLTSCGYDISNIPVYSSGEERYSKNSGK LFSIVKKNENVDIASWMHVGDNVHADILNAKKLGINTLHADWSEYNHGISNHWKAKDIIG ESICKTLLLKQVSAFHQNDPLNEIGFKVFGPLLLGYVSWLANQLKIHKIDKALFLARDAH LIYKIYNEYFSEEHVKCEYLYISRASAYMVGMTDWPMHRIWHLFGGKNKKSIKKILAIAG LDASEHISDIHHVGFPDEEYIPVSGEEHKVHWLINKLFPYILLKNTQHREVYADYFKTAC EGYKNIALIDVGWMGNIQSVFARSLGAQWAEKQIHGFYLATFAGANDNRSIYNKMFGWLT NYGHPNDKCDLFLSGGVEIMEFAMADNTGSTIGYKKTDNGIIPVREDSSGSEIEYLKKAA RLQSGIISFFEYVKPLIQKGNYAALSSVVLSEPFFELIARPSSAQLDALSSLTHSESAGS NAERIVLAKKLPLKDKLFPGENYIKELNASYWKEGFKRINRKKFWAKYN