Protein Info for GFF4626 in Xanthobacter sp. DMC5

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 487 transmembrane" amino acids 44 to 62 (19 residues), see Phobius details amino acids 96 to 116 (21 residues), see Phobius details amino acids 171 to 188 (18 residues), see Phobius details amino acids 200 to 221 (22 residues), see Phobius details amino acids 354 to 373 (20 residues), see Phobius details TIGR02745: cytochrome c oxidase accessory protein CcoG" amino acids 41 to 485 (445 residues), 524 bits, see alignment E=1.6e-161 PF12801: Fer4_5" amino acids 101 to 136 (36 residues), 30.7 bits, see alignment 8.9e-11 PF13746: Fer4_18" amino acids 224 to 332 (109 residues), 129.6 bits, see alignment E=2.2e-41 PF11614: FixG_C" amino acids 367 to 487 (121 residues), 95.8 bits, see alignment E=7.3e-31

Best Hits

Swiss-Prot: 48% identical to RDXB_RHOS4: Protein RdxB (rdxB) from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)

KEGG orthology group: None (inferred from 87% identity to xau:Xaut_0463)

Predicted SEED Role

"Type cbb3 cytochrome oxidase biogenesis protein CcoG, involved in Cu oxidation" in subsystem Biogenesis of cbb3-type cytochrome c oxidases or Terminal cytochrome C oxidases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (487 amino acids)

>GFF4626 hypothetical protein (Xanthobacter sp. DMC5)
MTALSTKSQDKKAPVVVSGDDDIPLYEARRQIYPQSVHGRFRTIKWVLLGITLGIYYLLP
FVRWDRGPDAPNQAVLIDFPARRFYFFFLEIWPQEFYYVAGLLILSALILFLMNAVAGRV
WCGYLCPQTVWTDLFMAVERLIEGDRRERMIADAQPWSIDKFAHKTLKHSIWLLIAWWTG
GAWVLYFADAPTLVVELATFQASAVAYMSIGVLTFTTYALAGHMREQVCTYMCPWPRIQA
ALTDEYALNVTYLYDRGEPRGSVKKAAVLREKGLPAGDCVDCGQCVAVCPTGVDIRQGLQ
LPCIQCGLCIDACNTVMHKIGRPGNLITYESEANLEARAAGKPFVQRILRPRTILYGVLI
AFVSGLMLTALIGRSTEGVSAIHDRNPLFVRLSSGAIRNAYTIRLINKKLEERTFILSVE
GVPDASLEVIGDNADGLTIGPDQTREVRVLVTTGDKLPPAASLPVTFRIRDKASGLSASV
TDHFIGP