Protein Info for GFF4626 in Variovorax sp. SCN45

Annotation: dTDP-Rha:A-D-GlcNAc-diphosphoryl polyprenol, A-3-L-rhamnosyl transferase WbbL

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 253 transmembrane" amino acids 223 to 243 (21 residues), see Phobius details PF00535: Glycos_transf_2" amino acids 60 to 174 (115 residues), 26.5 bits, see alignment E=1.4e-09 PF13641: Glyco_tranf_2_3" amino acids 62 to 216 (155 residues), 29.6 bits, see alignment E=1.6e-10 PF13506: Glyco_transf_21" amino acids 77 to 226 (150 residues), 26.6 bits, see alignment E=9.7e-10 PF13632: Glyco_trans_2_3" amino acids 89 to 203 (115 residues), 30.3 bits, see alignment E=9.7e-11 PF02709: Glyco_transf_7C" amino acids 161 to 202 (42 residues), 26.3 bits, see alignment 1.2e-09

Best Hits

KEGG orthology group: K07011, (no description) (inferred from 84% identity to vpe:Varpa_0796)

Predicted SEED Role

"dTDP-Rha:A-D-GlcNAc-diphosphoryl polyprenol, A-3-L-rhamnosyl transferase WbbL" in subsystem dTDP-rhamnose synthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (253 amino acids)

>GFF4626 dTDP-Rha:A-D-GlcNAc-diphosphoryl polyprenol, A-3-L-rhamnosyl transferase WbbL (Variovorax sp. SCN45)
MPTPPSPRPPITISIVSHGQLALVLPLLDQLDRHSRASTAKVVLTLNIPEPDMLAGRTWG
FEVEMIENASPKGFGSNHNQAFERCATPWFLVLNPDIRFDSDVLAPLLAQAAPDAGLLTP
RILEPGKNTPEPHRALLTPFEIVGRKKPGYVRPRVPAWIPGLFMLFRSEAYRKVGGFDER
FFMYGEDFDICARTRLEGWKLQVGEDLVARHDAQRESHRSKKYLYWHVTSLLKVWLSGSF
WRYRRLGTKTQAR