Protein Info for GFF4599 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: RNA polymerase sigma-70 factor, ECF subfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 425 PF04542: Sigma70_r2" amino acids 17 to 77 (61 residues), 24.6 bits, see alignment E=1.8e-09 PF20239: DUF6596" amino acids 187 to 288 (102 residues), 76.6 bits, see alignment E=1.6e-25

Best Hits

Predicted SEED Role

"RNA polymerase sigma-70 factor, ECF subfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (425 amino acids)

>GFF4599 RNA polymerase sigma-70 factor, ECF subfamily (Hydrogenophaga sp. GW460-11-11-14-LB1)
MNTRAAEAAALAARDTYGRLVAYLSWRWNDLAAAEDALGDALLKALERWPRDGVPAQPEG
WLLAVAHRALLQSARHQGVVQRLADDPVVRRLLPREDDAAPEPFLQAHPIPDNRLRLMLV
CAHPSIERSVRTPLMLQAVLGLDAQRIAAAFLVSPAAMAQRLVRAKQKIAQAGIRFEEPE
PADLPQRTHALLEAVYAAYGLAWERLGGSGELAAEALYLAELCEALLPGDAEARGLRALL
LFCESRRAARFVAAPDGSERFVPLHEQDTARWDHAQIAQADALLREAAALGQLGPYQLEA
AIQSAHAQRAVTGRVPWGGIVQLYEGLLQIAPTLGAHVGHAVALGTAHGAAQGLAALDGL
PEAEVRNHAPWWVARAHLLEQQRRWPDAAAALRHGMGLTEDPRLRAHLWYKLQALQAAPV
TGTPA