Protein Info for GFF4593 in Xanthobacter sp. DMC5

Annotation: Cyanuric acid amidohydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF09663: Amido_AtzD_TrzD
  • amino acids 5 to 351 (347 residues), 500.2 bits, E=1.7e-154
• TIGR02714: ring-opening amidohydrolases
  • amino acids 5 to 352 (348 residues), 424.4 bits, E=1.8e-131

Best Hits

Swiss-Prot: 85% identical to CAH_AZOC5: Cyanuric acid amidohydrolase (AZC_3892) from Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571)

KEGG orthology group: K03383, cyanuric acid amidohydrolase [EC: 3.5.2.15] (inferred from 85% identity to azc:AZC_3892)

Predicted SEED Role

"Cyanuric acid amidohydrolase (EC 3.5.2.15)" (EC 3.5.2.15)

MetaCyc Pathways

• cyanuric acid degradation II (5/5 steps found)
• cyanuric acid degradation I (4/5 steps found)
• superpathway of atrazine degradation (5/8 steps found)

KEGG Metabolic Maps

• Atrazine degradation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.2.15

Protein Sequence (364 amino acids)

>GFF4593 Cyanuric acid amidohydrolase (Xanthobacter sp. DMC5)
MPTAKVHRIPTASPDDVSGLAAAIASGAIAPEGILAIFGKTEGNGCVNDFSRGFAVAALQ
TLLRSHLGDAADEVCLVMSGGTEGGMAPHLLVFEVAEANTNGASPALAVGRAHTPDLPSE
HLGRMGQVRSVAEGVRRAMGAAGITDAGDVHFVQVKCPLLTAARVREAEARGATTATSDT
LKSMGLSRGASALGIALALGEIAEDALSDAAICADYGLWSGRASCSSGIELLGHEIVVLG
MSKSWTGPLAIAHAVMADAVDVAPVREAIDSLGGALGEDTIVLAKAEASRSGLIRGKRHT
MLDDSDISSTRHARAFVAGALAGVVGHTEIYVSGGAEHQGPDGGGPVAVILKSLADCARV
SLPE