Protein Info for GFF4576 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868
Annotation: Metal-dependent hydrolase YbeY, involved in rRNA and/or ribosome maturation and assembly
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to YBEY_SALTY: Endoribonuclease YbeY (ybeY) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
KEGG orthology group: K07042, probable rRNA maturation factor (inferred from 99% identity to seg:SG0672)Predicted SEED Role
"Metal-dependent hydrolase YbeY, involved in rRNA and/or ribosome maturation and assembly"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (157 amino acids)
>GFF4576 Metal-dependent hydrolase YbeY, involved in rRNA and/or ribosome maturation and assembly (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868) MSQVILDLQLACENHAGLPDEAQFQRWLDGVIPQFQEEAEVTIRLVDEAESHDLNLTYRG KDKPTNVLSFPFEAPAGIEMPLLGDLIICRQVVEQEAQEQSKPLEAHWAHMVVHGSLHLL GYDHIDDDEAEEMESLETEIMLAMGYEDPYIAEKIAE