Protein Info for GFF4554 in Xanthobacter sp. DMC5

Annotation: Calcium-transporting ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 940 transmembrane" amino acids 64 to 85 (22 residues), see Phobius details amino acids 91 to 111 (21 residues), see Phobius details amino acids 258 to 277 (20 residues), see Phobius details amino acids 289 to 315 (27 residues), see Phobius details amino acids 716 to 740 (25 residues), see Phobius details amino acids 749 to 769 (21 residues), see Phobius details amino acids 798 to 822 (25 residues), see Phobius details amino acids 837 to 855 (19 residues), see Phobius details amino acids 875 to 895 (21 residues), see Phobius details amino acids 907 to 927 (21 residues), see Phobius details PF00690: Cation_ATPase_N" amino acids 12 to 79 (68 residues), 64.3 bits, see alignment 1.9e-21 TIGR01494: HAD ATPase, P-type, family IC" amino acids 98 to 364 (267 residues), 131.2 bits, see alignment E=2e-42 amino acids 624 to 736 (113 residues), 113.3 bits, see alignment E=5.1e-37 PF00122: E1-E2_ATPase" amino acids 126 to 323 (198 residues), 166.3 bits, see alignment E=1.7e-52 PF00702: Hydrolase" amino acids 341 to 669 (329 residues), 64.1 bits, see alignment E=7e-21 PF13246: Cation_ATPase" amino acids 407 to 491 (85 residues), 70 bits, see alignment E=4.2e-23 PF08282: Hydrolase_3" amino acids 644 to 700 (57 residues), 23.4 bits, see alignment 1.4e-08 PF00689: Cation_ATPase_C" amino acids 755 to 929 (175 residues), 187.2 bits, see alignment E=7e-59

Best Hits

KEGG orthology group: None (inferred from 70% identity to xau:Xaut_4898)

Predicted SEED Role

"Ca ion P-type ATPase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (940 amino acids)

>GFF4554 Calcium-transporting ATPase (Xanthobacter sp. DMC5)
MLPIAVASSEPYRQSAEAVLAVLGSDAERGLSGAEAERRQAAFGPNLIATAPARSGWRRF
LDQFASALVLMLIAAGAISAAIWLHERGTPLPYEALAIFSIVLLNAAMGYVQEARAERAA
AALRRLSAAHARVIRDGETLSIDAAALVPGDVILVAEGDTIPADGRLLQATALQTVEAAL
TGESVPTAKDVAALPDGAEPADRANMVWSGTHAVYGHGRAVVTAVGMQTLMGRIAGLIEK
APQDETPLQRELERVGRVLGAVVLAIAGAVIGTILLMEGVRDLPQVLNVLILGVALAVAA
VPEGLPAVVTAVLSLGMQRMARNKAIVRRLAAVETLGSATVIASDKTGTLTRNEMTVRRV
VTASGSVALTGTGYAPDGALEFPDAPADRPALAQEVERALIAAERANNAILHEGADGFVV
HGDPTEGALIVAARKAGLSAPALDARFARLGEVPFSSERKLMSTLHSDAERPSHLILVTK
GAPDVLLAHCTGELRGEAEVPLGEARRTAILSANDALAGEALRTLGVAYRALPAPDLADG
AVTAEHERDLVFIGLIGMMDPPRPEARAAVAQAHAAGIRTLMMTGDHPATATVIAREVGI
PVDAGVVTGARIAALDEAGLDRVVAQASVYARVDPEHKLRIVAALRRAGETVAVTGDGVN
DAPALKAADIGIAMGTTGTDVSKEAADMVLADDNFATIVRAVAEGRAIFANIRKFLRYLL
SSNIGEVMTMVLGLLLAGRIGLSAAAEAAGGGVALPLLATQILWINLVTDGAPALALGID
PADGDVMTRPPRRRGEGVITGTMWAGIVFVGAVMAAGTLFVIDLSLPGGLVEGQGTLAYG
QTMAFTTLVLFQLFNVFNARSDTASAFVRPFANRWLIAAVAGSLLLHALVLYLPALQQAF
STVPLTARDWLLCAAVASSVIWTRELWKLAARALRRRRGV