Protein Info for GFF4551 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Twitching motility protein PilT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 381 TIGR01420: twitching motility protein" amino acids 1 to 340 (340 residues), 396.3 bits, see alignment E=6.3e-123 PF00437: T2SSE" amino acids 10 to 269 (260 residues), 134.4 bits, see alignment E=2.1e-43

Best Hits

KEGG orthology group: K02670, twitching motility protein PilU (inferred from 75% identity to pol:Bpro_1995)

Predicted SEED Role

"Twitching motility protein PilT" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (381 amino acids)

>GFF4551 Twitching motility protein PilT (Hydrogenophaga sp. GW460-11-11-14-LB1)
MERILRLMADKKASDVYLTAHAPAMIKINGQTIPVNSQVLPPDAPRNLLAEIVPPTRMEE
LQETGELNMAVPLDNLGNFRVSAFRQRGHIAVVIRYVSSEIPALDSLNVAPVLADLIMEK
RGLMLMVGATGAGKSTTLAAMIDHRNEQATGHILTIEDPIEYVYRNRKSVVNQREIGPDT
ASLQVALKNALRQAPDVILIGEIRDRETMSAAISYAQSGHLCLATLHANNSYQALNRILS
FYPVEVRPTMLGDLAAALRAIVSQRLLRTHTGGRVPAMEVMLNTSLIADLIQKADFSGVR
DAMEKSLAEGSQSFEQDLARLINDGLVARNEGLAHADSPNNLLWRLQNDFNATKASEAAQ
ASEEDAGDNATFTEFTLDVKF