Protein Info for GFF4522 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 424 transmembrane" amino acids 12 to 29 (18 residues), see Phobius details amino acids 45 to 68 (24 residues), see Phobius details amino acids 79 to 98 (20 residues), see Phobius details amino acids 104 to 123 (20 residues), see Phobius details amino acids 134 to 158 (25 residues), see Phobius details amino acids 165 to 186 (22 residues), see Phobius details amino acids 211 to 233 (23 residues), see Phobius details amino acids 247 to 267 (21 residues), see Phobius details amino acids 278 to 297 (20 residues), see Phobius details amino acids 303 to 324 (22 residues), see Phobius details amino acids 335 to 356 (22 residues), see Phobius details amino acids 364 to 384 (21 residues), see Phobius details PF07690: MFS_1" amino acids 28 to 348 (321 residues), 100.8 bits, see alignment E=4e-33

Best Hits

Swiss-Prot: 48% identical to CYNX_ECOLI: Cyanate transport protein CynX (cynX) from Escherichia coli (strain K12)

KEGG orthology group: K03449, MFS transporter, CP family, cyanate transporter (inferred from 49% identity to bph:Bphy_3444)

Predicted SEED Role

"Cyanate transport protein CynX" in subsystem Cyanate hydrolysis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (424 amino acids)

>GFF4522 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
VTQQARGRDGGAAFAFVIVLVALNLRAFLTSSSPLLEPIRLATGIGFHAVALLTVLPMFA
MGAMSLFGAAVGQRIGARGGIALGLAAIALACASRYVAGGAAALLWSAALAGAGVGLVQA
LMPGVVKQSYPARIGVMTGLYSAAIMGGGGLGAMASPWVAHAAGWHAGLAMWAVLAAAAL
LSWLAMRPASPVAAAPRQDLSWLRCFGSRRAWLLAVCFGLINGGYTSLVAWLPHFYAQQG
WSAQQGGSVLALMTAAQVLAALAMPALARSRGRDLRPWLMLTLAAQLAGFCALLFALPVP
AVAIAVVLGFGLGGAFSLCMVLALDHLPDPAQAGALAAFMQGVGFMIAALAPFVTGWVRE
HTGGFTMAWAYLAAVVVALLPLMLRFDPHRYAAATAGLFGARAPRQHGDAPSFPALDSAR
TGKP