Protein Info for PS417_23040 in Pseudomonas simiae WCS417

Updated annotation (from data): D-trehalose outer membrane porin
Rationale: Specific phenotype for trehalose (and conserved)
Original annotation: maltoporin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 406 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF02264: LamB" amino acids 25 to 405 (381 residues), 404.2 bits, see alignment E=5.4e-125

Best Hits

KEGG orthology group: K02024, maltoporin (inferred from 97% identity to pfs:PFLU5038)

Predicted SEED Role

"Maltoporin (maltose/maltodextrin high-affinity receptor, phage lambda receptor protein)" in subsystem Maltose and Maltodextrin Utilization or Trehalose Uptake and Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U675 at UniProt or InterPro

Protein Sequence (406 amino acids)

>PS417_23040 D-trehalose outer membrane porin (Pseudomonas simiae WCS417)
MKTTIKLGLVASCLGLPFGAQALEFAGYLRSGAGTSTGSGPQQCFQLPGAQTKYRLGNEC
EQYAELELRQDLLTLDDGSVLSVDAMASLYNKYDRALKFQGENNGSARMPQMYAQWSNLP
SLNGGSLWAGRRYYKRNDIHISDFYYWNQSATGGGIEDVLIGDLKYSYAISRKDNLYQKE
YATRHDFNVAGFKTNPGGELELGLSYIEKAGGRDTNSGWALTAQHVQKPFLGGKNKFALQ
YGEGPGTGLGYTGNTFLDKSSKSYRAVEFFDWQVTPRFGGQIEAVYQKDIRPGSQDQTWM
SLGVRPAYAISEQFKLVTELGHDQVDATGGTRKLSKFTFAPTWSPKGPEFWARPEVRLYY
TYATWNKAAKRAANELAAGSALSDTGSYGTARHGSNVGVQVEYWWK