Protein Info for GFF4496 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Ferric enterobactin transport system permease protein FepG (TC 3.A.1.14.2)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 329 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 62 to 80 (19 residues), see Phobius details amino acids 92 to 110 (19 residues), see Phobius details amino acids 116 to 137 (22 residues), see Phobius details amino acids 144 to 166 (23 residues), see Phobius details amino acids 192 to 210 (19 residues), see Phobius details amino acids 236 to 262 (27 residues), see Phobius details amino acids 275 to 294 (20 residues), see Phobius details amino acids 302 to 323 (22 residues), see Phobius details PF01032: FecCD" amino acids 20 to 323 (304 residues), 285.6 bits, see alignment E=2.2e-89

Best Hits

Swiss-Prot: 87% identical to FEPG_ECOLI: Ferric enterobactin transport system permease protein FepG (fepG) from Escherichia coli (strain K12)

KEGG orthology group: K02015, iron complex transport system permease protein (inferred from 99% identity to spt:SPA2143)

MetaCyc: 87% identical to ferric enterobactin ABC transporter membrane subunit FepG (Escherichia coli K-12 substr. MG1655)
ABC-10-RXN [EC: 7.2.2.17]

Predicted SEED Role

"Ferric enterobactin transport system permease protein FepG (TC 3.A.1.14.2)" in subsystem Siderophore Enterobactin (TC 3.A.1.14.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.2.2.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (329 amino acids)

>GFF4496 Ferric enterobactin transport system permease protein FepG (TC 3.A.1.14.2) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MFLSRRLIVSCLLLAAGCFAIGLWSLQSGAVPLETGQIIAALLGDAPRNITLVVTEWRLP
RVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLTAIALA
AMAGGIVTSLIVWLLAWRNGIETFRLIIIGIGIRAMLVAFNTWLLLQASLETALTAGLWN
AGSLNGLTWAKTWPSAPLIMVMLTGAALLVRRMRLLEMGDDSACALGVSVERSRLMLMLV
AVSLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQSALCGALLLLAADACAQQLFM
PYQLPVGVVTVSLGGIYLIVLLIQESRKK