Protein Info for GFF4495 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868
Annotation: ABC-type Fe3+-siderophore transport system, ATPase component
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 92% identical to FEPC_ECOLI: Ferric enterobactin transport ATP-binding protein FepC (fepC) from Escherichia coli (strain K12)
KEGG orthology group: K02013, iron complex transport system ATP-binding protein [EC: 3.6.3.34] (inferred from 100% identity to seh:SeHA_C0702)MetaCyc: 92% identical to ferric enterobactin ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-10-RXN [EC: 7.2.2.17]
Predicted SEED Role
No annotation
Isozymes
Compare fitness of predicted isozymes for: 3.6.3.34
Use Curated BLAST to search for 3.6.3.34 or 7.2.2.17
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (264 amino acids)
>GFF4495 ABC-type Fe3+-siderophore transport system, ATPase component (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868) MTESVARLRGDQLTLGYGSYTVAKNLNVSIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPV DGHVWLDGEQIQRYASKEVARRIGLLAQNATTPGDITVQELVARGRYPHQPLFTRWRKED ADAVASAMRATGITSLAAQSVDTLSGGQRQRAWIAMVLAQETSIMLLDEPTTWLDISHQI DLLELLSDLNREKGYTLAAVLHDLNQACRYATHLIALREGNIVAQGAPKEIVTAELIEKI YGLRCMIIDDPVAGTPLVVPLGRR