Protein Info for PS417_22940 in Pseudomonas simiae WCS417

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 437 transmembrane" amino acids 36 to 52 (17 residues), see Phobius details amino acids 60 to 82 (23 residues), see Phobius details amino acids 94 to 114 (21 residues), see Phobius details amino acids 120 to 145 (26 residues), see Phobius details amino acids 159 to 183 (25 residues), see Phobius details amino acids 194 to 213 (20 residues), see Phobius details amino acids 245 to 265 (21 residues), see Phobius details amino acids 284 to 305 (22 residues), see Phobius details amino acids 314 to 333 (20 residues), see Phobius details amino acids 339 to 361 (23 residues), see Phobius details amino acids 377 to 395 (19 residues), see Phobius details amino acids 406 to 425 (20 residues), see Phobius details PF00083: Sugar_tr" amino acids 23 to 229 (207 residues), 90.7 bits, see alignment E=1.1e-29 amino acids 258 to 436 (179 residues), 46.3 bits, see alignment E=3.1e-16 PF07690: MFS_1" amino acids 30 to 292 (263 residues), 52.8 bits, see alignment E=3.2e-18 amino acids 284 to 429 (146 residues), 46.4 bits, see alignment E=2.8e-16

Best Hits

Swiss-Prot: 56% identical to YHJE_ECOLI: Inner membrane metabolite transport protein YhjE (yhjE) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 98% identity to pfs:PFLU5016)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UKD7 at UniProt or InterPro

Protein Sequence (437 amino acids)

>PS417_22940 MFS transporter (Pseudomonas simiae WCS417)
MSTTYNEAAPAAAPTNSTARVATASIVGTAIEFYDFYIYATAAALVIGPVFFPQTSGTAQ
MLASFLTFGIAFIARPLGSALFGHFGDRIGRKSTLVASLLLMGVCTTLIGLLPGYDSIGA
WAPILLCVLRFGQGLGLGGEWGGAALLATENAPKGKRAWFGMFPQLGPSIGFLAANGLFL
ILAMSLSDEQFRSWGWRIPFILSAALVMVGLYARLKLHETPVFANAVAKEAPVKVPLVEL
FSQHWLPVLLGAASMVVCYALFYITTAFSLSYGVSTLGYSRETFLGLLCFAVLFMGLATP
LAALASDRFGRKPVLIVGALLAILSGFTMEPLLTHGSTWAVALFLALELFLMGVTFAPMG
AMLPELFPTRVRYTGASAAYNLGGIVGASAAPFFATKLVAMGGLSYVGGYVSAAALLSLI
AVLCLKETRDNDLNKVA