Protein Info for GFF4470 in Variovorax sp. SCN45

Annotation: Cell division protein FtsQ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 262 transmembrane" amino acids 16 to 38 (23 residues), see Phobius details PF08478: POTRA_1" amino acids 43 to 112 (70 residues), 50.6 bits, see alignment E=1.9e-17 PF03799: FtsQ_DivIB_C" amino acids 116 to 238 (123 residues), 76.1 bits, see alignment E=4e-25

Best Hits

Swiss-Prot: 37% identical to FTSQ_THIA3: Cell division protein FtsQ (ftsQ) from Thiomonas arsenitoxydans (strain DSM 22701 / CIP 110005 / 3As)

KEGG orthology group: K03589, cell division protein FtsQ (inferred from 92% identity to vpe:Varpa_0982)

Predicted SEED Role

"Cell division protein FtsQ" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (262 amino acids)

>GFF4470 Cell division protein FtsQ (Variovorax sp. SCN45)
MADSIPAPFDVKLMNIVANIAFAMVALMLLAAGAWWVLRQPFFPIVGIKVDGEVTHNNAV
TLRANVAPQLKGNFFTIDLLRARTAFESVPWVRSAVVRREFPNKLRVTLTEQVPVAIWGD
EAGSKLINGFGDVFEANVAEVDDNLPRLDGPIEQAGQVLGMYRVLQPQFQPYDFSIDELT
LSSRGSWKVVLDTGAEIELGRGQGEEVTARLQRFLKTVTQVAGQYHRTVADVEGADLRHN
DAYALRLRGVTTVSPEAPRRIK