Protein Info for GFF4468 in Sphingobium sp. HT1-2

Annotation: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 636 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 197 to 217 (21 residues), see Phobius details PF00970: FAD_binding_6" amino acids 286 to 384 (99 residues), 55 bits, see alignment E=1.3e-18 PF00175: NAD_binding_1" amino acids 395 to 500 (106 residues), 67.3 bits, see alignment E=2.8e-22 PF00111: Fer2" amino acids 558 to 626 (69 residues), 64.2 bits, see alignment E=1.3e-21

Best Hits

KEGG orthology group: None (inferred from 98% identity to sjp:SJA_C1-05160)

Predicted SEED Role

"Flavodoxin reductases (ferredoxin-NADPH reductases) family 1" in subsystem Anaerobic respiratory reductases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (636 amino acids)

>GFF4468 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 (Sphingobium sp. HT1-2)
MSRRISLRRLSLGCAIALSLSAGAGAQEGEDHAAHHGAGMPAGGGMSAPASSGSSDMAKM
MNPMMDRMINGEGENEHGHESRRTGFISQLLAFPALDEAARQRVAAQAGERVSTGLAMIN
AASADGARATTVSARLDAARRLREGTDLFRSGTAAQGAIGGLQPPREVGLAWLRDQLDID
QAAPGHADHWFGISPSHLLLMLFLGLVSATLIALQIFRLRRIGAIAGGVATAKTSEKPEP
KAVPPAAKFAPAPAPVAGSAGLASSNAAAPAGASLRKPKSWAGQLRVVQIVRETPSVLTF
RLADPAADRLPFDFLPGQFLQVEVEPEAGKTARRSYTIASSPTQRAYVELTVKREEQGVV
SRYLHDKVVADDLLKVSGPFGAFTFTGTDAQSIVLIAGGVGITPMMSVLRYLTDTAWKGD
IFFFYGARSTEEFVFRDELERLERRFPNLHVVAAMQRAPGTVWMGPEGPITREMILAAVP
EIASRRIHMCGPPAMMGAMRGVLAELGVPEAQLHTEAFGPASLPADHEDLEVKPAPAPAA
KPAPSAEVAPSTVTFSVSGVSAALPADETVLEAAEGAGVEIPYACRAGTCGACVVKLLQG
EVTMEVESGLAPADKAQGYVLACQAKGTGTPLVVEA