Protein Info for GFF4460 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 114 TIGR00377: anti-anti-sigma factor" amino acids 1 to 103 (103 residues), 70 bits, see alignment E=7.2e-24 PF01740: STAS" amino acids 4 to 105 (102 residues), 69.6 bits, see alignment E=1.8e-23 PF13466: STAS_2" amino acids 14 to 93 (80 residues), 46.2 bits, see alignment E=4.2e-16

Best Hits

Swiss-Prot: 33% identical to BTRV_BORBR: Putative anti-sigma factor antagonist BtrV (btrV) from Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)

KEGG orthology group: None (inferred from 39% identity to rrs:RoseRS_2160)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (114 amino acids)

>GFF4460 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV (Hydrogenophaga sp. GW460-11-11-14-LB1)
MQITLTPHDAIAVLAITGSIDSLNADELAQRFAQAQAQGHVRLVADFSLVNYTSSAGLRS
LLGAVKSCRLGGGDLRVAAVQPQVNRVLEIAGFTSILNIYPDVRLAVESFTEAA