Protein Info for GFF4443 in Variovorax sp. SCN45

Annotation: Cytochrome c-type biogenesis protein ResA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 184 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF00578: AhpC-TSA" amino acids 57 to 163 (107 residues), 62 bits, see alignment E=8.2e-21 PF08534: Redoxin" amino acids 58 to 171 (114 residues), 69.1 bits, see alignment E=5.6e-23 PF13905: Thioredoxin_8" amino acids 68 to 161 (94 residues), 39.4 bits, see alignment E=9.7e-14

Best Hits

KEGG orthology group: None (inferred from 90% identity to vpe:Varpa_1005)

Predicted SEED Role

"Cytochrome c-type biogenesis protein ResA" in subsystem Biogenesis of c-type cytochromes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (184 amino acids)

>GFF4443 Cytochrome c-type biogenesis protein ResA (Variovorax sp. SCN45)
MTSSPTRRGMLYAGVAAAAAAAGLGGAWWKERGSSSSAGGGEQLDAAFWGQSFERPEGGD
LVLSSLRGKPLLLNFWATWCPPCVEEMPMIDAFFREHGANGWQVVGLAIDQPSAVRKFLQ
RTPVTYPTGLAGLQGTELVKNLGNTGGGLPFTLVLNANGSVAARKMGKLETTDLDTWRRE
LVRG