Protein Info for GFF4427 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868
Annotation: Allantoin permease
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 92% identical to ALLP_ECOLI: Putative allantoin permease (ybbW) from Escherichia coli (strain K12)
KEGG orthology group: K10975, allantoin permease (inferred from 99% identity to sea:SeAg_B0568)MetaCyc: 92% identical to allantoin transporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-444
Predicted SEED Role
"Allantoin permease" in subsystem Allantoin Utilization
MetaCyc Pathways
- allantoin degradation IV (anaerobic) (8/9 steps found)
- allantoin degradation to glyoxylate II (5/5 steps found)
- allantoin degradation to glyoxylate III (5/5 steps found)
- allantoin degradation to ureidoglycolate II (ammonia producing) (4/4 steps found)
- superpathway of allantoin degradation in plants (6/8 steps found)
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (484 amino acids)
>GFF4427 Allantoin permease (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868) MEHQRELYQQRGYSEDLLPKTETQRNWKAFNYFTLWMGSVHNVPNYVMVGGFFILGLSTF NIMLAIIISALFIAAAMVMNGAAGSKYGVPFAMILRGSYGVRGALFPGLLRGGIAAIMWF GLQCYAGSLAFLILIGKIWPGFLTLGGDFKLLGLSLPGLITFLIFWIINVGIGFGGGKVL NKFTAILNPCIYIVFGGMAIWAISLVGIGPILDYLPSGVQKAEHSGFLFLVVINAVVAVW AAPAVSASDFTQNAHSFRAQALGQTLGLIVAYILFAVASVCIIAGASIHYGMDTWNVLDI VQRWDSLFASFFAVLVILMTTISTNATGNIIPAGYQIAALAPTKLNYKNGVMIASIISLL ICPWKLMENQDSIYLFLDIIGGMLGPVIGVMLAHYFVVMRGKINLDELYTASGDYKYYDN GFNLTAFSVTLVAVILSLGGKFIPFMEPLSRVSWFVGVIVAFVAYALLKKRTGFENTGEK KLAG