Protein Info for GFF4410 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: FIG000875: Thioredoxin domain-containing protein EC-YbbN

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 293 PF13728: TraF" amino acids 13 to 96 (84 residues), 27.5 bits, see alignment E=6.6e-10 PF00085: Thioredoxin" amino acids 15 to 116 (102 residues), 70.2 bits, see alignment E=3.4e-23 PF14559: TPR_19" amino acids 133 to 199 (67 residues), 70.5 bits, see alignment E=3e-23 PF14561: TPR_20" amino acids 204 to 293 (90 residues), 99.4 bits, see alignment E=3e-32

Best Hits

Swiss-Prot: 95% identical to CNOX_ECOLI: Chaperedoxin (cnoX) from Escherichia coli (strain K12)

KEGG orthology group: K05838, putative thioredoxin (inferred from 99% identity to sew:SeSA_A0568)

Predicted SEED Role

"FIG000875: Thioredoxin domain-containing protein EC-YbbN"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (293 amino acids)

>GFF4410 FIG000875: Thioredoxin domain-containing protein EC-YbbN (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
VTQTKESDAMSVQNIVNINESNLQQTLEQSMTTPVLFYFWSERSQHCLQLTPVLESLAAQ
YHGQFILAKLDCDAEQMIAAQFGLRAIPTVYLFQNGQPVDGFQGPQPEEAIRALLDKVLP
REEELKAQQAMQLMQEGNYIDALPLLKDAWQLSSQNSEIGLLLAEAQIALNRSEEAEAVL
KTIPLQDQDTRYQGLVAQIELLKQAADTPEIQQLQQQVADNPQDAALATQLALQLHQVGR
NEEALELLFSHLRKDLTAAEGQTRKTFQEILAALGTGDALASKYRRQLYALLY