Protein Info for GFF4372 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Various polyols ABC transporter, periplasmic substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 449 PF01547: SBP_bac_1" amino acids 67 to 342 (276 residues), 102.3 bits, see alignment E=5.4e-33 PF13416: SBP_bac_8" amino acids 71 to 377 (307 residues), 105.3 bits, see alignment E=5.1e-34

Best Hits

KEGG orthology group: None (inferred from 53% identity to vei:Veis_1879)

Predicted SEED Role

"Various polyols ABC transporter, periplasmic substrate-binding protein" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (449 amino acids)

>GFF4372 Various polyols ABC transporter, periplasmic substrate-binding protein (Hydrogenophaga sp. GW460-11-11-14-LB1)
MATQIEDRTSAPAQSLTTEETSHSRRRLLGGGATGAALMALGAPAVHAQTKTIRFLNAEP
GRESVRALRVAAAEYEKLTGVKVQVDTVPPDEAYSKLQASISSGTPYDIGTLAFAGHMLI
LAEAGKLAPMTKLIEKSKWGPRILFPVKGEHYWYPYDYNFCWMYYRKDLYQQKGLKVPTT
FDQMAENCKVLTGDGKFGVGHPLGANSAMQWMSIGYLWADGAKLLDDDFKLVIDNAEMKP
KMIRYLDFMKKLQPSMPTGMTQALFGTVLGQYSGGQIAHAPYAGRLMEVLEDRAPDLAGK
TGFFMYPDSTGKGQAVNHGYDGWVLLNTPMKDEAYKFMEWFTERHYINFLHSAPLHFQPP
RLDVYDDPQWRAHPLVEKHAELVEFMRGILTNKDVTIRSIDTEGSRIDLRPGKMFETFAI
SEAVQNRLLKDMPAAEAVDIMAKKYRTVL