Protein Info for GFF4369 in Xanthobacter sp. DMC5

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1237 PF05378: Hydant_A_N" amino acids 34 to 213 (180 residues), 186.7 bits, see alignment E=6.4e-59 PF01968: Hydantoinase_A" amino acids 232 to 528 (297 residues), 364.2 bits, see alignment E=9.6e-113 PF19278: Hydant_A_C" amino acids 549 to 701 (153 residues), 34 bits, see alignment E=3.9e-12 PF02538: Hydantoinase_B" amino acids 725 to 1231 (507 residues), 666.8 bits, see alignment E=4.1e-204

Best Hits

KEGG orthology group: K01469, 5-oxoprolinase (ATP-hydrolysing) [EC: 3.5.2.9] (inferred from 84% identity to azc:AZC_0168)

Predicted SEED Role

"5-oxoprolinase (EC 3.5.2.9)" in subsystem Glutathione: Biosynthesis and gamma-glutamyl cycle (EC 3.5.2.9)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1237 amino acids)

>GFF4369 hypothetical protein (Xanthobacter sp. DMC5)
MSSDDVKTSAAAETDAAAPPSPSAAAPSPAPWEFWIDRGGTFTDIVGRKPDGSLVAHKVL
SENPEAYRDAAVHGIRELLGLPAGAAIPPGLVSAVKMGTTVATNALLERKGDRTLLVTTR
GFKDALRIGYQARPKIFAKKIVLPDMLFESVLEVDERVRADGTVEAAPDLATVRAALEQA
KADGIAAVAIVFMHGYRFPEHEQQVAALAREIGFPQVSVSHEVSPLIKLVGRGDTTVADA
YLSPILRRYVRQVAEELSGGREGEGQAASEAIRLMFMMSSGGLTAADLFQGKDALLSGPA
GGVVGAAETGALAGFNRIIGFDMGGTSTDVCHYDGELETAFDTEVAGVRIRAPMMRIHTV
AAGGGSILHYDGARFRVGPDSAGANPGPACYRRGGPLAVTDANVMLGKLIPDYFPKIFGP
AQDQPLDAEVVRGKFSALAEEIGGGRSPEEVADGFVTIAVENMANAIKKISVERGYDVTR
YALNCFGGAGGQHACLVADALGMTKVLLHPFSGLLSAYGMGLASVRAQRTRAVGEEMTTT
LIPGLVELKAELAAATQAELATQGIRTDSILTEAKAHLRYGGTDTALPVQLADIAAMTAE
FETKHRAQFGFVSPEKTIVVEALEVISAGGGAGIAEPDLPLNAGTPSDTSQTRFFARGAW
HDAPVVKRENFKPGMNLQGPAIVIEPNQTVVVEKGWRAEVSAKNHLILTRTEKLLRSEAV
GTHADPVMLEVFNNLFMSIAEQMGVTLQNTAYSVNIKERLDFSCAVFSAEGDLVANAPHM
PVHLGSMDRSVETVIRENAGDIHPGDVFALNAPYNGGTHLPDITVVTPVFDDAGKAILFW
VASRGHHSDVGGVAPGSMSPLATHIEEEGVYIDNFKLVSEGTFREAELRHLLTSARYPAR
NPVQNIADLKAQIAANEKGVRELLKMIDTFGLDVVQAYMGHVQDNAAESVRRVLDRLDDC
SFHYEMDQGTVIKVKISVDKEKREATVDFTGTSPQQPTNFNAPAPVTRAAVLYVFRVMVE
DEIPMNAGCLRPIRIVVPEGCMLSPVYPAAVVAGNVETSQAVTNCLFGALKAMSASQGTM
NNLTFGNDIYQYYETICSGSPAGPGFDGTDGVHVHMTNSRLTDPEVLETRFPVLLEDFHI
RPGSGGRGRWHAGSGTYRRIRFLETMDCALLSSHRRVHPFGVDGGEKGQLGEGFVRRLDG
STEVLQGCDQKVLEAGEAVIIVTPTGGGYGDAKLRER