Protein Info for PS417_22130 in Pseudomonas simiae WCS417

Updated annotation (from data): glucose/xylose ABC transporter, ATPase component
Rationale: Specifically important for utilization of D-glucose 6-phosphate and D-xylose. Glucokinase (PS417_22685) is important for glucose-6-phosphate utilization, which implies that it is hydrolyzed to glucose before uptake.
Original annotation: sugar ABC transporter ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 386 PF00005: ABC_tran" amino acids 21 to 163 (143 residues), 121.3 bits, see alignment E=1.2e-38 PF17912: OB_MalK" amino acids 237 to 291 (55 residues), 43.3 bits, see alignment 1.4e-14 PF08402: TOBE_2" amino acids 284 to 357 (74 residues), 42.2 bits, see alignment E=1.8e-14 PF03459: TOBE" amino acids 304 to 356 (53 residues), 37 bits, see alignment 8.1e-13

Best Hits

KEGG orthology group: K02023, multiple sugar transport system ATP-binding protein (inferred from 96% identity to pfs:PFLU4843)

Predicted SEED Role

"Glucose ABC transporter, ATP-binding subunit (EC 3.6.3.-)" (EC 3.6.3.-)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U0S1 at UniProt or InterPro

Protein Sequence (386 amino acids)

>PS417_22130 glucose/xylose ABC transporter, ATPase component (Pseudomonas simiae WCS417)
MATLELRNVNKTYGAGLPDTLKNIELSIKEGEFLILVGPSGCGKSTLMNCIAGLETITGG
AIMIGDQDVSGMSPKDRDIAMVFQSYALYPTMSVRENIEFGLKIRKMPQADIDAEVARVA
KLLQIEHLLNRKPGQLSGGQQQRVAMGRALARRPKIYLFDEPLSNLDAKLRVEMRTEMKL
MHQRLKTTTVYVTHDQIEAMTLGDKVAVMKDGIIQQFGTPKEIYNNPANQFVASFIGSPP
MNFVPLRLQRKDGRLVALLDSGQARCELALNTTEAGLEDRDVILGLRPEQIMLAAGEGDS
ASSIRAEVQVTEPTGPDTLVFVQLNDTKVCCRLAPDVAPQVGETLTLQFDPSKVLLFDAN
TGERLGTASSLPAQGHADNVAQFKGR